SBRT: An Opportunity to Improve Quality of Life for Oligometastatic Prostate Cancer
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چکیده
منابع مشابه
SBRT: An Opportunity to Improve Quality of Life for Oligometastatic Prostate Cancer
OBJECTIVE Oligometastatic prostate cancer is a limited metastatic disease state in which potential long-term control is still possible with the use of targeted therapies such as surgery or stereotactic body radiation therapy (SBRT). SBRT may as well potentially prolong the time before the initiation of androgen deprivation therapy (ADT) and docetaxel chemotherapy for oligometastatic prostate ca...
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OPINION STATEMENT The mainstay of treatment for men with three or fewer non-castrate metastatic lesions outside of the prostate remains morbid palliative androgen deprivation therapy. We believe there is now a significant body of retrospective literature to suggest a survival benefit if these men have radical treatment to their primary tumour alongside 'metastasis-directed therapy' to the metas...
متن کاملQuality of Life and Toxicity after SBRT for Organ-Confined Prostate Cancer, a 7-Year Study
OBJECTIVES Stereotactic body radiation therapy (SBRT) yields excellent disease control for low- and intermediate-risk prostate cancer by delivering high doses of radiation in a small number of fractions. Our report presents a 7-year update on treatment toxicity and quality of life (QOL) from 515 patients treated with prostate SBRT. METHODS From 2006 to 2009, 515 patients with clinically local...
متن کاملOligometastatic prostate cancer: Metastases-directed therapy?
Since the introduction of anatomical and functional imaging with multiparametric magnetic resonance imaging and choline or prostate-specific membrane antigen positron emission tomography-computed tomography, we are able to diagnose a previously unknown disease, the oligometastatic prostate cancer after local therapy. Reports on surgical and radiation treatment for low-volume metastatic recurren...
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The term oligometastasis (o-mets) was first coined by Hellman & Weichselbaum [4]. The data available at the time suggested a stepwise progression of cancer from localized disease to an intermediate state of malignancy and then to widespread metastases. The practical implication of this suggested paradigm shift was that some patients could potentially be cured with definitive local therapies or ...
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ژورنال
عنوان ژورنال: Frontiers in Oncology
سال: 2015
ISSN: 2234-943X
DOI: 10.3389/fonc.2015.00101